Immunological Unresponsiveness in Allergic Contact Dermatitis to Dinitrochlorobenzene in Guinea Pigs

Elicitation of Allergic Contact Dermatitis in the Guinea Pig

When one or two drops of a dilute, non-irritating solution of 2,4-dinitrochlorobenzene (DNCB) is applied to a small area of skin of the intact guinea pig, about 20 per cent of the applied material, or some derivative of it, is soon excreted in urine. In normal, as well as in specifically sensitized guinea pigs, DNCB at the site of local application becomes rapidly bound to skin protein through ...

[Allergic contact dermatitis to cosmetics].

INTRODUCTION Contact dermatitis to cosmetics is a common problem in the general population, although its prevalence appears to be underestimated. We reviewed cases of allergic contact dermatitis to cosmetics diagnosed in our dermatology department over a 7-year period with a view to identifying the allergens responsible, the frequency of occurrence of these allergens, and the cosmetic products ...

[Allergic contact dermatitis to footwear in children].

Allergic Contact Dermatitis in Children

Contact allergy (CA), a pathologic response after (usually repeated) contact to environmental substances of low molecular weight occurring in a varying proportion of exposed persons, often results in clinical disease, allergic contact dermatitis (ACD), which can be disabling. CA is diagnosed by patch testing, a technique of controlled exposure of patients suspected to have ACD to a standardized...

Contact dermatitis in dentistry

Contact dermatitis can affect dentists, orthodontists, technicians, nurses and the patients. The increase of dental patients in recent years caused an increase in reports of dermatitis and other allergies in patients and in dentists too. With changes in dental materials through years, allergy and contact reactions in persons in contact with new allergens had been increased. So dentists and derm...